Neurons derived from different brain regions are inherently different in vitro: a novel multiregional brain-on-a-chip

Different Brain Regions are Infected with Fungi in Alzheimer’s Disease

The possibility that Alzheimer's disease (AD) has a microbial aetiology has been proposed by several researchers. Here, we provide evidence that tissue from the central nervous system (CNS) of AD patients contain fungal cells and hyphae. Fungal material can be detected both intra- and extracellularly using specific antibodies against several fungi. Different brain regions including external fro...

a novel mu rhythm based brain computer interface design that uses a programmable system on chip

this paper describes the system design of a portable and economical mu rhythm based brain computer interface which employs cypress semiconductors programmable system on chip (psoc). by carrying out essential processing on the psoc, the use of an extra computer is eliminated, resulting in considerable cost savings. microsoft visual studio 2005 and psoc designer 5.01 are employed in developing th...

Datumetine Preferentially Upregulates NMDAR Signalling Pathways in Different Brain Regions of Mice

Background: We earlier reported that datumetine possesses binding affinity with NMDAR and that 14-day exposure to datumetine altered NMDAR signalling by mimicking glutamate toxicity. Here, we investigated the potential neuroprotective effect of a single shot of a low dose of datumetine administration in BALB/c mice. Results: Relative to Veh, datumetine downregulate the expression of CamKIIα i...

[Toxic effect of formaldehyde on mouse different brain regions].

The aim of this study was to explore the mechanism of the nervous system lesions induced by formaldehyde (FA). Male Balb/c mice were exposed to gaseous formaldehyde for 7 days (8 h/d) with three different concentrations (0, 0.5 and 3.0 mg/m(3)). A group of animals injected with the nitric oxide synthase inhibitor L-NMMA (0.01 mL/g) was also set and exposed to 3.0 mg/m(3) FA. The concentrations ...

Growing into a different brain